Structure via PubChem · Public domain (PubChem)
D-(+)-neopterin
Sign in to saveAlso known as D-erythro-neopterin
Neopterin is an organic compound belonging to the pteridine class of heterocyclic compounds.
Chemical data
- Formula
- C9H11N5O4
- Molecular weight
- 253.22 g/mol
- IUPAC name
- 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-3H-pteridin-4-one
- SMILES
- C1=C(N=C2C(=O)NC(=NC2=N1)N)[C@@H]([C@@H](CO)O)O
- InChIKey
- BMQYVXCPAOLZOK-XINAWCOVSA-N
- XLogP
- -3.5
- Polar surface area
- 154 Ų
- H-bond donors
- 5
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
20 papers- An Fe2+-dependent cyclic phosphodiesterase catalyzes the hydrolysis of 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate in methanopterin biosynthesis.Biochemistry · 2009
- Synthesis of enzymatically active D-7,8-dihydroneopterin-3'-triphosphate.Biochemical and biophysical research communications · 1988
- [Pterin chemistry. 43. Synthesis of D-neopterin-3'-phosphate and D-neopterin-2',3'-cyclophosphate. Considerations on the biogenesis of biopterin].Helvetica chimica acta · 1973
- Interleukin-6, vitamin D & diabetes risk-factors modified by a short-term yoga-based lifestyle intervention in overweight/obese individuals.The Indian journal of medical research · 2015
- Analysis for fully oxidized neopterin in serum by high-performance liquid chromatography.Clinical chemistry · 1992
via PubMed
Wikidata facts
- Mass
- 253.081
Show 4 more facts
- chemical formula
- C₉H₁₁N₅O₄
- canonical SMILES
- O=C1N=C(N=C2NC=C(N=C12)C(O)C(O)CO)N
- isomeric SMILES
- O=C1C=2C(NC=C([C@@H]([C@@H](CO)O)O)N2)=NC(N)=N1
- found in taxon
- Firebug
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Biosynthesis
- Neopterin as disease marker
- References
- External links
Neopterin is an organic compound belonging to the pteridine class of heterocyclic compounds.
Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation. In humans neopterin follows a circadian (daily) and circaseptan (weekly) rhythm.
Excerpted from Wikipedia’s “D-(+)-neopterin” article, available under the CC BY-SA 4.0 licence.