demethylation
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Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule. A common way of demethylation is the replacement of a methyl group by a hydrogen atom, resulting in a net loss of one carbon and two hydrogen atoms.
Research
29,342 papers- Active DNA Demethylation in Plants.International journal of molecular sciences · 2019
- Control of histone demethylation by nuclear-localized α-ketoglutarate dehydrogenase.Science (New York, N.Y.) · 2023
- RNA m(6)A regulates transcription via DNA demethylation and chromatin accessibility.Nature genetics · 2022
- Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers.Molecular cell · 2025
- Enhancing demethylation-induced differentiation in IDH-mutant glioma.Neuro-oncology · 2022
via PubMed
Wikidata facts
- Subclass of
- metabolism
Show 2 more facts
- exact match
- purl.obolibrary.org/obo/GO_0070988
- opposite of
- methylation
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
6 sectionsContents
- In biochemistry
- Biomass processing
- In organic chemistry
- ''N''-demethylation
- See also
- References
Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule. A common way of demethylation is the replacement of a methyl group by a hydrogen atom, resulting in a net loss of one carbon and two hydrogen atoms.
The counterpart of demethylation is methylation.
Excerpted from Wikipedia’s “demethylation” article, available under the CC BY-SA 4.0 licence.