File:Dexamethasone_structure.svg · Wikimedia Commons · See Wikimedia Commons
دگزامتازون
Sign in to saveAlso known as Decadron®, desametasone, fluormethylprednisolone, DXM833
ترکیب شیمیایی
OverviewAI-generated
Dexamethasone is a chemical compound with the formula C₂₂H₂₉FO₅. Its molecular mass is listed as 392.19990224799994, while its weight is recorded as 392.5. The substance has a defined daily dose of 1.5.
Physicochemical properties include a water/octanol partition coefficient of 1.83 and an xlogp value of 1.9. The compound features a topological polar surface area of 94.8, with three hydrogen bond donors and six hydrogen bond acceptors. It carries a charge of 0.
Literature references for dexamethasone number 88,713. The subject is referenced by 1,357 other encyclopedia articles.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443584169
- Drug.image
- Dexamethasone structure.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula of dexamethasone
- Drug.image2
- Dexamethasone 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Ball-and-stick model of the dexamethasone molecule
- Drug.caption
- Dexamethasone molecular structure
- Drug.tradename
- Decadron, Ozurdex, Dexycu, others
- Drug.MedlinePlus
- a682792
- Drug.DailyMedID
- Dexamethasone
- Drug.pregnancy_AU
- A
- Drug.routes_of_administration
- By mouth, intravenous, intramuscular, subcutaneous, intraosseous, intravitreal, eye drop
- Drug.caption2
- 3D representation of dexamethasone
- Drug.ATC_prefix
- A01
- Drug.ATC_suffix
- AC02
via Wikipedia infobox
Chemical data
- Formula
- C22H29FO5
- Molecular weight
- 392.5 g/mol
- IUPAC name
- (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
- InChIKey
- UREBDLICKHMUKA-CXSFZGCWSA-N
- XLogP
- 1.9
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1958
- Admin. routes
- oral, parenteral, topical
- Indications
- eye inflammation, multiple myeloma, pain, prostate carcinoma
via ChEMBL · EBI
Research
88,713 papers- [Perioperative dexamethasone].Der Anaesthesist · 2019
- Selinexor-Bortezomib-Dexamethasone: A Review in Previously Treated Multiple Myeloma.Targeted oncology · 2023
- DEXAMETHASONE INTRAVITREAL INJECTION IN DIABETIC PATIENTS UNDERGOING CATARACT SURGERY: An Updated Literature Review.Retina (Philadelphia, Pa.) · 2025
- [Dexamethasone - Risk Factor for Wound Healing Disorder and Hyperglycaemia?].Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS · 2025
- Intravenous Dexamethasone as an Analgesic: A Literature Review.AANA journal · 2018
via PubMed
Wikidata facts
- Has part
- hydrogen
- Mass
- 392.19990224799994
- Has use
- medication
Show 12 more facts
- medical condition treated
- COVID-19
- found in taxon
- Colletotrichum
- chemical formula
- C₂₂H₂₉FO₅
- canonical SMILES
- CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
- isomeric SMILES
- C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
- Commons category
- Dexamethasone
- has characteristic
- bitterness
- World Health Organisation international non-proprietary name
- dexamethasone
- subject has role
- essential medicine
- partition coefficient water/octanol
- 1.83
- defined daily dose
- 1.5
- stereoisomer of
- betamethasone
via Wikidata · CC0