xylometazoline

Key facts

Drug.Verifiedfields

changed

Drug.Watchedfields

changed

Drug.verifiedrevid

459852622

Drug.image

Xylometazoline.svg

Drug.image_class

skin-invert-image

Drug.width

225px

Drug.tradename

Otrivin, Otrivine, others

Drug.MedlinePlus

a608026

Drug.DailyMedID

Xylometazoline

Drug.dependency_liability

Moderate

Drug.routes_of_administration

intranasal (spray or drops)

Drug.class

α1 and α2 Adrenergic receptor agonist,Decongestant

Drug.ATC_prefix

R01

Drug.ATC_suffix

AA07

Drug.legal_UK

General sales list (GSL, OTC)

Drug.legal_US

OTC

Drug.elimination_half life

2–3 hours

Drug.excretion

Urinary

via Wikipedia infobox

Chemical data

Formula

C16H24N2

Molecular weight

244.37 g/mol

IUPAC name

2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole

SMILES

CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C

InChIKey

HUCJFAOMUPXHDK-UHFFFAOYSA-N

XLogP

3.2

Polar surface area

24.4 Ų

H-bond donors

1

H-bond acceptors

1

Formal charge

0

via PubChem

• Xylometazoline.2006
• Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold.Current medical research and opinion · 2010
• Comprehensive evaluation of xylometazoline hydrochloride formulations: Ex-vivo and in-vitro studies.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2024
• Use of xylometazoline in hospitalised infants: is it safe? A retrospective cohort study.Archives of disease in childhood · 2023
• Hemorrhagic stroke caused by xylometazoline poisoning.Journal of forensic sciences · 2024

via PubMed