Structure via PubChem · Public domain (PubChem)
deksmetilfenidat
Sign in to saveAlso known as FOC124, D-TMP, d-threo-methylphenidate, (+)-threo-methylphenidate, methyl (R)-phenyl[(R)-piperidin-2-yl]acetate
Dexmethylphenidate, sold under the brand name Focalin among others, is a central nervous system (CNS) stimulant used in the treatment of attention deficit hyperactivity disorder (ADHD) in those over the age of five years. It is taken by mouth. The immediate-release formulation lasts up to five hours while the extended-release formulation lasts up to twelve hours. It is the more active enantiomer of methylphenidate. Methylphenidate has been shown to be more effective than atomoxetine and superior in treating ADHD symptoms when compared.
Chemical data
- Formula
- C14H19NO2
- Molecular weight
- 233.31 g/mol
- IUPAC name
- methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate
- SMILES
- COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2
- InChIKey
- DUGOZIWVEXMGBE-CHWSQXEVSA-N
- XLogP
- 0.2
- Polar surface area
- 38.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2001
- Admin. routes
- oral
- Indications
- attention deficit hyperactivity disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- methylphenidate
- Mass
- 233.141579
- Has use
- medication
Show 10 more facts
- Commons category
- Dexmethylphenidate
- name
- dexmethylphenidate
- chemical formula
- C₁₄H₁₉NO₂
- significant drug interaction
- tranylcypromine
- medical condition treated
- attention deficit hyperactivity disorder
- canonical SMILES
- COC(=O)C(C1CCCCN1)C2=CC=CC=C2
- isomeric SMILES
- COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2
- World Health Organisation international non-proprietary name
- dexmethylphenidate
- defined daily dose
- 15.0
- subject has role
- nootropic
Sources (7)
via Wikidata · CC0