डाइक्लोरोफेन

Also known as Dichlorophene, C13H10Cl2O2, ATC code P02DX02, 2,2'-Methylenebis(4-chlorophenol)

Dichlorophen is an anticestodal agent, fungicide, germicide, and antimicrobial agent. It is used in combination with toluene for the removal of parasites such as ascarids, hookworms, and tapeworms from dogs and cats. In 2025, dichlorophen was reported to function as a tubulin binding mitotic inhibitor.

Chemical data

Formula: C13H10Cl2O2
Molecular weight: 269.12 g/mol
IUPAC name: 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol
SMILES: C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O
InChIKey: MDNWOSOZYLHTCG-UHFFFAOYSA-N
XLogP: 4.3
Polar surface area: 40.5 Å²
H-bond donors: 2
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: Helminthiasis

via ChEMBL · EBI

Research

208 papers

Antimicrobial and Anti-Biofilm Activity of Dichlorophen-Functionalized Gold Nanoparticles Against Carbapenem-Resistant Enterobacteriaceae.International journal of nanomedicine · 2025
Identification of Bithionol, Dichlorophen, and Miconazole as Antibacterial Agents against Acinetobacter calcoaceticus.ACS omega · 2020
Electrooxidation of chlorophene and dichlorophen by reactive electrochemical membrane: Key determining factors of removal efficiency.Environmental research · 2024
A life-threatening dichlorophen poisoning case: clinical features and kinetics study.Clinical toxicology (Philadelphia, Pa.) · 2013
Cestodes.Antibiotics and chemotherapy · 1981

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 268.006

Show 4 more facts

chemical formula: C₁₃H₁₀Cl₂O₂
canonical SMILES: C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O
Commons category: Dichlorophen
melting point: 174

Sources (3)

via Wikidata · CC0

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via Wikidata sitelinks · CC0