Structure via PubChem · Public domain (PubChem)
dihydralazine
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Dihydralazine is a prescription drug with antihypertensive properties. It functions by combating the effects of adrenaline, and by expanding the blood vessels so as to enable smoother flow of blood by decreasing the pressure. It is generally administered orally, and is available in the form of tablets. It belongs to the hydrazinophthalazine chemical class. It has very similar effects to hydralazine.
Chemical data
- Formula
- C8H10N6
- Molecular weight
- 190.21 g/mol
- IUPAC name
- (4-hydrazinylphthalazin-1-yl)hydrazine
- SMILES
- C1=CC=C2C(=C1)C(=NN=C2NN)NN
- InChIKey
- VQKLRVZQQYVIJW-UHFFFAOYSA-N
- XLogP
- 0.2
- Polar surface area
- 102 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- hypertension, aortic stenosis
via ChEMBL · EBI
Research
594 papers- The change in the pharmacological significance of dihydralazine (Germany) and hydralazine (USA).Naunyn-Schmiedeberg's archives of pharmacology · 2026
- [Dihydralazine-induced hepatitis].Schweizerische medizinische Wochenschrift · 1977
- Drug-induced immunotoxicity.European journal of drug metabolism and pharmacokinetics · 1998
- [Dihydralazine hepatitis].Presse medicale (Paris, France : 1983) · 1985
- Dihydralazine infusion effects.Obstetrics and gynecology · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 190.097
- Has use
- medication
Show 7 more facts
- Commons category
- Dihydralazine
- chemical formula
- C₈H₁₀N₆
- canonical SMILES
- C1=CC=C2C(=C1)C(=NN=C2NN)NN
- isomeric SMILES
- C1=CC=C\2C(=C1)/C(=N\N)/NN/C2=N\N
- defined daily dose
- 75
- subject has role
- antihypertensive drug
- World Health Organisation international non-proprietary name
- dihydralazine
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Side effects
- Contraindications
- Other important information on intake
- See also
- References
- Further reading
Dihydralazine is a prescription drug with antihypertensive properties. It functions by combating the effects of adrenaline, and by expanding the blood vessels so as to enable smoother flow of blood by decreasing the pressure. It is generally administered orally, and is available in the form of tablets. It belongs to the hydrazinophthalazine chemical class. It has very similar effects to hydralazine.
== Side effects == Headache Loss of appetite Nausea Vomiting Diarrhea Palpitations Increased heart rate Angina pectoris
Excerpted from Wikipedia’s “dihydralazine” article, available under the CC BY-SA 4.0 licence.