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iproclozide
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Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued. It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.
Chemical data
- Formula
- C11H15ClN2O2
- Molecular weight
- 242.7 g/mol
- IUPAC name
- 2-(4-chlorophenoxy)-N'-propan-2-ylacetohydrazide
- SMILES
- CC(C)NNC(=O)COC1=CC=C(C=C1)Cl
- InChIKey
- GGECDTUJZOXAAR-UHFFFAOYSA-N
- XLogP
- 2
- Polar surface area
- 50.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- major depressive disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 242.082
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₁H₁₅ClN₂O₂
- World Health Organisation international non-proprietary name
- iproclozide
- canonical SMILES
- CC(C)NNC(=O)COC1=CC=C(C=C1)Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued. It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.
== See also == Hydrazine (antidepressant)
Excerpted from Wikipedia’s “iproclozide” article, available under the CC BY-SA 4.0 licence.
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