Structure via PubChem · Public domain (PubChem)
safrazine
Sign in to saveAlso known as Safra
Safrazine (Safra) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was introduced as an antidepressant in the 1960s, but has since been discontinued alongside several old generation MAOIs in favor of the invention of RIMAs and more efficacious treatments for depression in general.
In the Vinony graph
Within Vinony's link graph, safrazine is referenced by 476 other articles, and connects out to L-tyrosine, enzyme inhibitor and hydrazide.
It sits within the topics Benzodioxoles, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C11H16N2O2
- Molecular weight
- 208.26 g/mol
- IUPAC name
- 1-(1,3-benzodioxol-5-ylmethyl)-2-propan-2-ylhydrazine
- SMILES
- CC(C)NNCC1=CC2=C(C=C1)OCO2
- InChIKey
- LHXBSYGNYYTTRM-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 42.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 208.121178
- Has use
- medication
Show 2 more facts
- chemical formula
- C₁₁H₁₆N₂O₂
- canonical SMILES
- CC(C)NNCC1=CC2=C(C=C1)OCO2
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Safrazine (Safra) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was introduced as an antidepressant in the 1960s, but has since been discontinued alongside several old generation MAOIs in favor of the invention of RIMAs and more efficacious treatments for depression in general.
== See also == Hydrazine (antidepressant)
Excerpted from Wikipedia’s “safrazine” article, available under the CC BY-SA 4.0 licence.