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dimenoxadol

Structure via PubChem · Public domain (PubChem)

EntityQ4161658· pop 7· linked from 824 articles

dimenoxadol

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Also known as dimenoxadole, estocin

Dimenoxadol (INN; also known as dimenoxadole (BAN) or dimenoxadole; brand name Estocin in Russia) is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

Chemical data

Formula
C20H25NO3
Molecular weight
327.4 g/mol
IUPAC name
2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate
SMILES
CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCCN(C)C
InChIKey
RHUWRJWFHUKVED-UHFFFAOYSA-N
XLogP
3.6
Polar surface area
38.8 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Has part
carbon
Mass
327.183444
Show 2 more facts
chemical formula
C₂₀H₂₅NO₃
canonical SMILES
CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCCN(C)C
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • Synthesis
  • References

Dimenoxadol (INN; also known as dimenoxadole (BAN) or dimenoxadole; brand name Estocin in Russia) is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

It was invented in Germany in the 1950s, and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

Excerpted from Wikipedia’s “dimenoxadol” article, available under the CC BY-SA 4.0 licence.

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