Gene data
DPYS- Name
- dihydropyrimidinase
- Type
- protein-coding
- Position
- 104,327,415–104,467,111 (−)
- Aliases
- DHP, DHPase
- Ensembl
- ENSG00000147647
- RefSeq RNA
- NM_001385.3, XM_005250818.4, XM_006716518.4, XM_011516903.4, XM_017013167.3
- RefSeq protein
- NP_001376.1, XP_005250875.1, XP_006716581.1, XP_011515205.1, XP_016868656.1
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Pyrimidine metabolism - Homo sapiens (human)beta-Alanine metabolism - Homo sapiens (human)Pantothenate and CoA biosynthesis - Homo sapiens (human)Drug metabolism - other enzymes - Homo sapiens (human)MetabolismMetabolism of nucleotidesPyrimidine catabolismNucleotide catabolismFluoropyrimidine ActivityPyrimidine metabolism
via MyGene.info
Gene · Ensembl
dihydropyrimidinase
- Symbol
- DPYS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:104,327,415-104,467,111
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 20359
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1807
- genomic end
- 104467055
- genomic start
- 105342552
- chromosome
- human chromosome 8
- cytogenetic location
- 8q22.3
via Wikidata · CC0