Also known as CDD, cytidine deaminase
protein-coding gene in the species Homo sapiens
Gene data
CDA- Name
- cytidine deaminase
- Type
- protein-coding
- Position
- 20,588,898–20,618,913 (+)
- Aliases
- CDD
- Ensembl
- ENSG00000158825
- RefSeq RNA
- NM_001785.3
- RefSeq protein
- NP_001776.1
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytidine deaminase
- Symbol
- CDA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:20,588,898-20,618,913
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI