Structure via PubChem · Public domain (PubChem)
ethiofencarb
Sign in to saveAlso known as Croneton, 2-((Ethylthio)methyl)phenol methylcarbamate, 2-((Ethylthio)methyl)phenyl methylcarbamate, alpha-(Ethylthio)-o-tolyl methylcarbamate, alpha-Ethylthio-o-tolyl methylcarbamate
Ethiofencarb is a carbamate insecticide which is useful in controlling aphids on hard and soft fruits and some vegetables. It is not as dangerous as organophosphorous pesticides, but is considered highly toxic to humans in the UK, moderately toxic under US EPA classification, and highly toxic to aquatic life.
Chemical data
- Formula
- C11H15NO2S
- Molecular weight
- 225.31 g/mol
- IUPAC name
- [2-(ethylsulfanylmethyl)phenyl] N-methylcarbamate
- SMILES
- CCSCC1=CC=CC=C1OC(=O)NC
- InChIKey
- HEZNVIYQEUHLNI-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 63.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 225.082
- Has use
- insecticide
Show 3 more facts
- chemical formula
- C₁₁H₁₅NO₂S
- Commons category
- Ethiofencarb
- canonical SMILES
- CCSCC1=CC=CC=C1OC(=O)NC
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
6 sectionsContents
- Mechanism of action
- Environmental fate
- Metabolism
- Safety
- Regulation
- References
Ethiofencarb is a carbamate insecticide which is useful in controlling aphids on hard and soft fruits and some vegetables. It is not as dangerous as organophosphorous pesticides, but is considered highly toxic to humans in the UK, moderately toxic under US EPA classification, and highly toxic to aquatic life.
==Mechanism of action== Carbamates are effective insecticides because of their ability to inhibit acetylcholinesterase (AChE) in the nervous system. Carbamate pesticides are less dangerous to humans than organophosphorus pesticides because carbamylation of the enzyme is unstable, and the regeneration of AChE is faster compared to a phosphorylated enzyme. Therefore the dose required to produce minimum symptoms of poisoning and a lethal dose is substantially larger for carbamate compounds than for organophosphorus compounds.
Excerpted from Wikipedia’s “ethiofencarb” article, available under the CC BY-SA 4.0 licence.