etifoxine
Sign in to saveAlso known as HOE 36-801, HOE-36801
Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. Administration is by mouth. Side effects associated with etifoxine use include slight drowsiness, headache, skin eruptions, and allergic reactions. In rare cases, etifoxine has been linked to severe skin and liver toxicity, as well as menstrual bleeding between periods. Unlike benzodiazepines, etifoxine does not cause seda
Research
116 papers- Etifoxine for pain patients with anxiety.The Korean journal of pain · 2015
- Translocator Protein Ligand Etifoxine Attenuates MPTP-Induced Neurotoxicity.Frontiers in molecular neuroscience · 2022
- TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice.Brain research bulletin · 2020
- Anxiolytics targeting GABA(A) receptors: Insights on etifoxine.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2018
- GABAergic Effects of Etifoxine and Alprazolam Assessed by Double Pulse TMS.Pharmacopsychiatry · 2023
via PubMed
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Encyclopedic overview
16 sectionsContents
- Medical uses
- Available forms
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Names
- Availability
- See also
- References
- Further reading
- External links
Etifoxine, sold under the trade name Stresam among others, is a nonbenzodiazepine anxiolytic agent, primarily indicated for short-term management of adjustment disorder, specifically instances of situational depression accompanied by anxiety, such as stress-induced anxiety. Administration is by mouth.
Side effects associated with etifoxine use include slight drowsiness, headache, skin eruptions, and allergic reactions. In rare cases, etifoxine has been linked to severe skin and liver toxicity, as well as menstrual bleeding between periods. Unlike benzodiazepines, etifoxine does not cause sedation or lack of coordination. Etifoxine acts as a ligand for translocator proteins.
Excerpted from Wikipedia’s “etifoxine” article, available under the CC BY-SA 4.0 licence.