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fenclofenac

Structure via PubChem · Public domain (PubChem)

EntityQ3742414· pop 7· linked from 217 articles

fenclofenac

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Fenclofenac is a nonsteroidal anti-inflammatory drug (NSAID) previously used in rheumatism. It has mild immunosuppressive effects and may displace thyroid hormone from its binding protein. It can also cause lichen planus.

Chemical data

Formula
C14H10Cl2O3
Molecular weight
297.1 g/mol
IUPAC name
2-[2-(2,4-dichlorophenoxy)phenyl]acetic acid
SMILES
C1=CC=C(C(=C1)CC(=O)O)OC2=C(C=C(C=C2)Cl)Cl
InChIKey
IDKAXRLETRCXKS-UHFFFAOYSA-N
XLogP
4.8
Polar surface area
46.5 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Withdrawn
Max clinical phase
Approved
Molecule type
Small molecule
First approval
1978

via ChEMBL · EBI

Research

94 papers

via PubMed

Wikidata facts

Mass
296.001
Show 4 more facts
chemical formula
C₁₄H₁₀Cl₂O₃
canonical SMILES
C1=CC=C(C(=C1)CC(=O)O)OC2=C(C=C(C=C2)Cl)Cl
Commons category
Fenclofenac
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Fenclofenac is a nonsteroidal anti-inflammatory drug (NSAID) previously used in rheumatism. It has mild immunosuppressive effects and may displace thyroid hormone from its binding protein. It can also cause lichen planus.

Due to its side effects it was withdrawn from the UK and US in the 1980s.

Excerpted from Wikipedia’s “fenclofenac” article, available under the CC BY-SA 4.0 licence.

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