FFAR1
Sign in to saveAlso known as FFA1R, GPCR40, GPR40, free fatty acid receptor 1
protein-coding gene in the species Homo sapiens
Gene data
FFAR1- Name
- free fatty acid receptor 1
- Type
- protein-coding
- Position
- 35,347,902–35,353,864 (+)
- Aliases
- FFA1R, GPCR40, GPR40
- Ensembl
- ENSG00000126266
- RefSeq RNA
- NM_005303.3, XM_047438698.1, XM_054320732.1
- RefSeq protein
- NP_005294.1, XP_047294654.1, XP_054176707.1
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009].
Gene Ontology
Biological process
G protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayphospholipase C-activating G protein-coupled receptor signaling pathwaypositive regulation of cytosolic calcium ion concentrationpositive regulation of cytosolic calcium ion concentrationpositive regulation of insulin secretionpositive regulation of insulin secretion
Molecular function
Pathways
Insulin secretion - Homo sapiens (human)MetabolismSignal TransductionIntegration of energy metabolismPeptide hormone metabolismSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)GPCR downstream signallingMetabolism of proteins
via MyGene.info
Gene · Ensembl
free fatty acid receptor 1
- Symbol
- FFAR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:35,347,902-35,353,864
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Available in 6 languages
via Wikidata sitelinks · CC0