fludiazepam
Sign in to saveAlso known as Erispan, 7-chloro-5-(O-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one, Fludiazepamum
Fludiazepam, marketed under the brand name Erispan (エリスパン) is a potent benzodiazepine and 2ʹ-fluoro derivative of diazepam, originally developed by Hoffmann-La Roche in the 1960s. It is marketed in Japan and Taiwan. It exerts its pharmacological properties via enhancement of GABAergic inhibition. Fludiazepam has 4 times more binding affinity for benzodiazepine receptors than diazepam. It possesses anxiolytic, anticonvulsant, sedative, hypnotic and skeletal muscle relaxant properties. Fludiazepam has been used recreationally.
Wikidata facts
- Mass
- 302.062219
Show 5 more facts
- chemical formula
- C₁₆H₁₂ClFN₂O
- canonical SMILES
- CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F
- Commons category
- Fludiazepam
- defined daily dose
- 0.75
- MCN code
- 2933.91.31
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Fludiazepam, marketed under the brand name Erispan (エリスパン) is a potent benzodiazepine and 2ʹ-fluoro derivative of diazepam, originally developed by Hoffmann-La Roche in the 1960s. It is marketed in Japan and Taiwan. It exerts its pharmacological properties via enhancement of GABAergic inhibition. Fludiazepam has 4 times more binding affinity for benzodiazepine receptors than diazepam. It possesses anxiolytic, anticonvulsant, sedative, hypnotic and skeletal muscle relaxant properties. Fludiazepam has been used recreationally.
== See also == Diazepam Diclazepam (the 2ʹ-chloro analog) Difludiazepam (the 2',6'-difluoro derivative) Flunitrazepam (the 7-nitro analog) Flualprazolam (the triazolo derivative) Ro20-8552