GGT1
Sign in to saveAlso known as CD224, D22S672, D22S732, GGT, GGT 1, GTG, gamma-glutamyltransferase 1, GGTD
protein-coding gene in the species Homo sapiens
Gene data
GGT1- Name
- gamma-glutamyltransferase 1
- Type
- protein-coding
- Position
- 24,588,696–24,629,011 (+)
- Aliases
- CD224, D22S672, D22S732, GGT, GGT 1, GGTD, GTG
- Ensembl
- ENSG00000100031
- RefSeq RNA
- NM_001032364.2, NM_001032365.2, NM_001288833.2, NM_005265.3, NM_013421.3
- RefSeq protein
- NP_001275762.1, NP_038265.2, NP_038347.2
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
gamma-glutamyltransferase 1
- Symbol
- GGT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:24,588,696-24,629,011
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68450
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2678
- cytogenetic location
- 22q11.23
- chromosome
- human chromosome 22
- genomic start
- 24979718
- genomic end
- 25024972
- expressed in
- gonad
Sources (3)
via Wikidata · CC0