GGT1

Also known as CD224, D22S672, D22S732, GGT, GGT 1, GTG, gamma-glutamyltransferase 1, GGTD

protein-coding gene in the species Homo sapiens

In the Vinony graph

Vinony's link graph records 363 inbound references to GGT1, and connects out to Q180686, Ensembl genome database project and CD1.

Vinony files it under Clusters of differentiation and Genes on human chromosome 22.

Vinony links it to 5 Wikipedia language editions.

Gene data

GGT1

Name: gamma-glutamyltransferase 1
Type: protein-coding
Position: 24,588,696–24,629,011 (+)
Aliases: CD224, D22S672, D22S732, GGT, GGT 1, GGTD, GTG
Ensembl: ENSG00000100031
RefSeq RNA: NM_001032364.2, NM_001032365.2, NM_001288833.2, NM_005265.3, NM_013421.3
RefSeq protein: NP_001275762.1, NP_038265.2, NP_038347.2

The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014].