Skip to content
GeneQ14911955· pop 5· linked from 506 articles

Also known as PGQTL2, gastric inhibitory polypeptide receptor

protein-coding gene in the species Homo sapiens

Gene data

GIPR
Name
gastric inhibitory polypeptide receptor
Type
protein-coding
Aliases
PGQTL2

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011].

via MyGene.info

Gene · Ensembl

gastric inhibitory polypeptide receptor

Symbol
GIPR
Biotype
Protein coding
Organism
Homo sapiens
Location
19:45,668,207-45,683,722
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
20081
genetic association
obesity
found in taxon
Homo sapiens
genomic end
45683722
genomic start
45668221
cytogenetic location
19q13.32
Sources (6)

via Wikidata · CC0

Available in 5 languages

via Wikidata sitelinks · CC0