TRPA1
Sign in to saveAlso known as ANKTM1, FEPS, transient receptor potential cation channel subfamily A member 1, FEPS1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Mustard and Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 (and in mice and rats by the Trpa1) gene.
Gene data
TRPA1- Name
- transient receptor potential cation channel subfamily A member 1
- Type
- protein-coding
- Aliases
- ANKTM1, FEPS, FEPS1, p120
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7189
- exact match
- identifiers.org/ncbigene/8989
- genomic end
- 72075584
- genomic start
- 72932152
- cytogenetic location
- 8q21.11
Sources (4)
via Wikidata · CC0
~12 min read
Article
9 sectionsContents
- Structure
- Function
- Clinical significance
- Ligands
- Agonists
- Antagonists
- Gating modifiers
- References
- External links
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Mustard and Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 (and in mice and rats by the Trpa1) gene.
TRPA1 is an ion channel located on the plasma membrane of many human and animal cells. This ion channel is best known as a sensor for pain, cold and itch in humans and other mammals, as well as a sensor for environmental irritants giving rise to other protective responses (tears, airway resistance, and cough).