TRPA1
Sign in to saveAlso known as ANKTM1, FEPS, transient receptor potential cation channel subfamily A member 1, FEPS1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Mustard and Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 (and in mice and rats by the Trpa1) gene.
Gene data
TRPA1- Name
- transient receptor potential cation channel subfamily A member 1
- Type
- protein-coding
- Position
- 72,019,608–72,089,998 (−)
- Aliases
- ANKTM1, FEPS, FEPS1, p120
- Ensembl
- ENSG00000104321
- RefSeq RNA
- NM_007332.3, XM_011517624.3, XM_011517625.3, XM_054361455.1, XM_054361456.1
- RefSeq protein
- NP_015628.2, XP_011515926.1, XP_011515927.1, XP_054217430.1, XP_054217431.1
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transient receptor potential cation channel subfamily A member 1
- Symbol
- TRPA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:72,019,608-72,089,998
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7189
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8989
- genomic end
- 72075584
- genomic start
- 72932152
- chromosome
- human chromosome 8
- cytogenetic location
- 8q21.11
Sources (4)
via Wikidata · CC0
~12 min read
Encyclopedic overview
9 sectionsContents
- Structure
- Function
- Clinical significance
- Ligands
- Agonists
- Antagonists
- Gating modifiers
- References
- External links
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Mustard and Wasabi Receptor, is a protein that in humans is encoded by the TRPA1 (and in mice and rats by the Trpa1) gene.
TRPA1 is an ion channel located on the plasma membrane of many human and animal cells. This ion channel is best known as a sensor for pain, cold and itch in humans and other mammals, as well as a sensor for environmental irritants giving rise to other protective responses (tears, airway resistance, and cough).
Excerpted from Wikipedia’s “TRPA1” article, available under the CC BY-SA 4.0 licence.