GPR158

Also known as G protein-coupled receptor 158

Probable G-protein coupled receptor 158 (GPR158), also known as the metabotropic glycine receptor (mGlyR), is a protein that in humans is encoded by the GPR158 gene.

Gene data

GPR158

Name: G protein-coupled receptor 158
Type: protein-coding
Aliases: mGlyR

Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and protein localization to plasma membrane. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

via MyGene.info

Wikidata facts

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HomoloGene ID: 19381
exact match: identifiers.org/ncbigene/57512
genomic end: 25602229
genomic start: 25174802
cytogenetic location: 10p12.1

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Contents

Function
Clinical significance
Role in mood regulation
Role in prostate cancer
References

Probable G-protein coupled receptor 158 (GPR158), also known as the metabotropic glycine receptor (mGlyR), is a protein that in humans is encoded by the GPR158 gene.

==Function== This protein is an orphan class C GPCR. It is highly expressed in the brain, where it binds to RGS7, an inhibitor of Gi/o-coupled GPCR signaling, localizing it to the plasma membrane.