GPR25
Sign in to saveAlso known as G protein-coupled receptor 25
Probable G-protein coupled receptor 25 is a protein that in humans is encoded by the GPR25 gene.
Gene data
GPR25- Name
- G protein-coupled receptor 25
- Type
- protein-coding
This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. This gene has been linked to arterial stiffness. [provided by RefSeq, Nov 2012].
via MyGene.info
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/2848
- HomoloGene ID
- 3872
- genomic end
- 200843306
- genomic start
- 200872981
- cytogenetic location
- 1q32.1
Sources (4)
via Wikidata · CC0
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Article
5 sectionsContents
- Structure
- Tissue distribution
- Function
- References
- Further reading
Probable G-protein coupled receptor 25 is a protein that in humans is encoded by the GPR25 gene.
== Structure == It is a member of the G protein-coupled receptor (GPCR) family and it's well conserved in vertebrate evolution containing a canonical DRYLAVV motif in the third transmembrane sequence. It has a conserved negatively charged N-terminal extracellular peptide comprising a DY candidate sulfation site that is characteristic of many leukocyte chemoattractant receptors for positively charged polypeptides of the chemokine family.