Also known as RE2, G protein-coupled receptor 161
G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene. It is located on primary cilia and regulates embryonic development through suppression of the hedgehog signaling pathway. It appears to act as a mechanoreceptor and may not require an endogenous ligand for activation.
The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017].
via MyGene.info
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G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene. It is located on primary cilia and regulates embryonic development through suppression of the hedgehog signaling pathway. It appears to act as a mechanoreceptor and may not require an endogenous ligand for activation.
==References==
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).