GPR153
Sign in to saveAlso known as PGR1, G protein-coupled receptor 153
Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.
Gene data
GPR153- Name
- G protein-coupled receptor 153
- Type
- protein-coding
- Aliases
- PGR1
This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18662
- exact match
- identifiers.org/ncbigene/387509
- genomic end
- 6261098
- genomic start
- 6247353
- cytogenetic location
- 1p36.31
Sources (3)
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- References
- Further reading
Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.
==References==