GPR35
Sign in to saveAlso known as G protein-coupled receptor 35
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
Gene data
GPR35- Name
- G protein-coupled receptor 35
- Type
- protein-coding
- Position
- 240,605,404–240,633,159 (+)
- Ensembl
- ENSG00000178623
- RefSeq RNA
- NM_001195381.3, NM_001195382.3, NM_001394730.1, NM_005301.5
- RefSeq protein
- NP_001182310.1, NP_001182311.1, NP_001381659.1, NP_005292.2
Enables C-X-C chemokine receptor activity. Involved in several processes, including chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
G protein-coupled receptor 35
- Symbol
- GPR35
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:240,605,404-240,633,159
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3874
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2859
- genomic start
- 240605430
- chromosome
- human chromosome 2
- genomic end
- 240633159
- cytogenetic location
- 2q37.3
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Ligands
- Endogenous ligands
- Synthetic agonists
- Antagonists
- Clinical significance
- References
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
== Ligands ==
Excerpted from Wikipedia’s “GPR35” article, available under the CC BY-SA 4.0 licence.