HCRTR1
Sign in to saveAlso known as OX1R, Hypocretin (orexin) receptor 1, hypocretin receptor 1, ORXR1, OXR1
protein-coding gene in the species Homo sapiens
Gene data
HCRTR1- Name
- hypocretin receptor 1
- Type
- protein-coding
- Position
- 31,617,660–31,632,518 (+)
- Aliases
- ORXR1, OX1R, OXR1
- Ensembl
- ENSG00000121764
- RefSeq RNA
- NM_001525.3, XM_017001107.2, XM_024446605.2, XM_054336200.1, XM_054336201.1
- RefSeq protein
- NP_001516.2, XP_016856596.1, XP_024302373.1, XP_054192175.1, XP_054192176.1
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009].
Gene Ontology
Biological process
Molecular function
Pathways
Neuroactive ligand-receptor interaction - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)Peptide ligand-binding receptorsGPCR downstream signallingOrexin and neuropeptides FF and QRFP bind to their respective receptorsG alpha (q) signalling eventsGPCR ligand bindingPeptide GPCRs
via MyGene.info
Gene · Ensembl
hypocretin receptor 1
- Symbol
- HCRTR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:31,617,660-31,632,518
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI