FZD4
Sign in to saveAlso known as CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR
Frizzled-4 (Fz-4) is a protein that in humans is encoded by the FZD4 gene. Fz-4 has also been designated as CD344 (cluster of differentiation 344).
Gene data
FZD4- Name
- frizzled class receptor 4
- Type
- protein-coding
- Position
- 86,945,679–86,955,395 (−)
- Aliases
- CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4
- Ensembl
- ENSG00000174804
- RefSeq RNA
- NM_012193.4
- RefSeq protein
- NP_036325.2
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7325
- exact match
- identifiers.org/ncbigene/8322
- genomic end
- 86955395
- genomic start
- 86656721
- cytogenetic location
- 11q14.2
via Wikidata · CC0
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Article
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Frizzled-4 (Fz-4) is a protein that in humans is encoded by the FZD4 gene. Fz-4 has also been designated as CD344 (cluster of differentiation 344).
== Function ==