Skip to content
homochirality
EntityQ903478· pop 11· linked from 243 articles

homochirality

Sign in to save

Homochirality is a uniformity of chirality, or handedness. Objects are chiral when they cannot be superposed on their mirror images. For example, the left and right hands of a human are approximately mirror images of each other but are not their own mirror images, so they are chiral. In chemistry, chirality is a geometric property of some compounds and ions. These compounds exist in two different chiral conformations, enantiomers, often described as the left-handed and right-handed isomers of a compound (denoted by L- (levorotatory to the left) and D- (dextrorotatory to the right), respectivel

~26 min read

Article

24 sections
Contents
  • History of the term
  • In biology
  • Origins of biomolecular homochirality
  • Symmetry breaking
  • Deterministic theories
  • Parity Violation
  • Extraterrestrial origin of homochirality
  • Chance theories
  • Amplification
  • Theory
  • Experiments
  • Transmission
  • The hypothesized central dogma of biological homochirality
  • Ribose aminooxazoline (RAO), a critical RNA precursor molecule
  • Symmetry-breaking and chiral amplification of ribose aminooxazoline (RAO)
  • Propagating homochirality from nucleic acids through a chemical network
  • Possible prebiotic environments
  • Drawbacks
  • Biotic Theory
  • Optical resolution in racemic amino acids
  • See also
  • References
  • Further reading
  • External links

Homochirality is a uniformity of chirality, or handedness. Objects are chiral when they cannot be superposed on their mirror images. For example, the left and right hands of a human are approximately mirror images of each other but are not their own mirror images, so they are chiral. In chemistry, chirality is a geometric property of some compounds and ions. These compounds exist in two different chiral conformations, enantiomers, often described as the left-handed and right-handed isomers of a compound (denoted by L- (levorotatory to the left) and D- (dextrorotatory to the right), respectively, from how chiral molecules rotate plane-polarized light). The term homochiral is used to describe enantiopure samples of substances in which all the constituents are the same enantiomer.

Enantiomers have the same chemical properties in an achiral environment, so abiotic chemical processes typically produce racemic mixtures of chiral compounds, i.e., mixtures containing equal amounts of L- and D-isomers. However, many biologically-synthesized compounds are homochiral. For example, 19 of the 20 genetically-coded proteinogenic amino acids are left-handed, with exception of the achiral glycine, and biological sugars are right-handed.

Gallery (6)

Connections

Categories