File:Hydrocodone_skeletal.svg · Wikimedia Commons · See Wikimedia Commons
Hydrocodon
Sign in to saveAlso known as Zohydro®, Dihydrocodeinone, Idrocodone, Hydroconum, Hydrocone, 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one, (-)-Dihydrocodeinone
chemische Verbindung
OverviewAI-generated
Hydrocodone is a chemical compound with the formula C₁₈H₂₁NO₃. Its IUPAC name is (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one. The substance has a melting point of 198 and a defined daily dose of 15.
Chemical properties include a mass of 299.152 and a weight of 299.4. The compound has an xlogp of 2.2 and a tpsa of 38.8. It contains zero hydrogen bond donors and four hydrogen bond acceptors, with a charge of 0.
Hydrocodone is referenced by 1,275 other encyclopedia articles.
Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.excretion
- Urine
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443251358
- Drug.image
- Hydrocodone skeletal.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Hydrocodone-Spartan-PM3-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 225
- Drug.tradename
- Hysingla ER, Zohydro ER
- Drug.MedlinePlus
- a601006
- Drug.DailyMedID
- Hydrocodone
- Drug.dependency_liability
- High
- Drug.addiction_liability
- High
- Drug.class
- Opioid
- Drug.routes_of_administration
- Clinical: By mouthOthers: Intranasal, rectal
- Drug.ATC_prefix
- R05
- Drug.ATC_suffix
- DA03
via Wikipedia infobox
Chemical data
- Formula
- C18H21NO3
- Molecular weight
- 299.4 g/mol
- IUPAC name
- (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
- SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
- InChIKey
- LLPOLZWFYMWNKH-CMKMFDCUSA-N
- XLogP
- 2.2
- Polar surface area
- 38.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1943
- Admin. routes
- oral
- Indications
- pain, eye disease, Cough, injury
via ChEMBL · EBI
Research
1,669 papers- Hydrocodone bitartrate for chronic pain.Drugs of today (Barcelona, Spain : 1998) · 2015
- Hydrocodone Bitartrate ER (Hysingla(®) ER): A Review in Chronic Pain.Clinical drug investigation · 2016
- Hydrocodone extended-release: pharmacodynamics, pharmacokinetics and behavioral pharmacology of a controversy.Pharmacological research · 2015
- Extended-release hydrocodone (Hysingla ER) for pain.The Medical letter on drugs and therapeutics · 2015
- Hydrocodone: does it have a role in palliative care?Journal of opioid management · 2010
via PubMed
Wikidata facts
- Has part
- oxygen
- Mass
- 299.152
- Has use
- medication
Show 11 more facts
- chemical formula
- C₁₈H₂₁NO₃
- subject has role
- antitussive
- medical condition treated
- cough
- isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
- melting point
- 198
- canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)CC4
- World Health Organisation international non-proprietary name
- hydrocodone
- Commons category
- Hydrocodone
- defined daily dose
- 15
- found in taxon
- Papaver somniferum
- stylized name
- HYDROcodone
via Wikidata · CC0
Article · Deutsch
Hydrocodon oder Dihydrocodeinon ist ein Opioid, das mit dem Codein strukturverwandt ist und wie dieses zu den Derivaten des Morphins gehört. Als Monopräparat (wie etwa Dicodid) wirkt es als Analgetikum (Schmerzmittel) und als Antitussivum (Hustenmittel). In den USA wird der Arzneistoff hauptsächlich in Kombinationspräparaten mit Paracetamol (wie etwa Vicodin) oder Ibuprofen vertrieben.
Abstract from DBpedia / Wikipedia · CC BY-SA