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Also known as Zohydro®, Dihydrocodeinone, Idrocodone, Hydroconum, Hydrocone, 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one, (-)-Dihydrocodeinone, Hydrocodon

Hydrocodone, also known as dihydrocodeinone, is a semi-synthetic opioid used to treat pain and as a cough suppressant. It is taken by mouth. Typically, it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone for pain severe enough to require an opioid and in combination with homatropine methylbromide to relieve cough. It is also available by itself in a long-acting form sold under the brand name Zohydro ER, among others, to treat severe pain of a prolonged duration. Hydrocodone is a controlled drug: in the United States, it is classified as a Schedule II Controlle

OverviewAI-generated

Hydrocodone is a chemical compound with the formula C₁₈H₂₁NO₃. Its IUPAC name is (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one. The substance has a melting point of 198 and a defined daily dose of 15.

Chemical properties include a mass of 299.152 and a weight of 299.4. The compound has an xlogp of 2.2 and a tpsa of 38.8. It contains zero hydrogen bond donors and four hydrogen bond acceptors, with a charge of 0.

Hydrocodone is referenced by 1,275 other encyclopedia articles.

Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.excretion: Urine
Drug.Watchedfields: changed
Drug.verifiedrevid: 443251358
Drug.image: Hydrocodone skeletal.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: Hydrocodone-Spartan-PM3-3D-balls.png
Drug.image_class2: bg-transparent
Drug.width2: 225
Drug.tradename: Hysingla ER, Zohydro ER
Drug.MedlinePlus: a601006
Drug.DailyMedID: Hydrocodone
Drug.dependency_liability: High
Drug.addiction_liability: High
Drug.class: Opioid
Drug.routes_of_administration: Clinical: By mouthOthers: Intranasal, rectal
Drug.ATC_prefix: R05
Drug.ATC_suffix: DA03

via Wikipedia infobox

Chemical data

Formula: C18H21NO3
Molecular weight: 299.4 g/mol
IUPAC name: (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
InChIKey: LLPOLZWFYMWNKH-CMKMFDCUSA-N
XLogP: 2.2
Polar surface area: 38.8 Å²
H-bond donors: 0
H-bond acceptors: 4
Formal charge: 0