File:Hydrocodone_skeletal.svg · Wikimedia Commons · See Wikimedia Commons
hidrocodona
Sign in to saveAlso known as Zohydro®, Dihydrocodeinone, Idrocodone, Hydroconum, Hydrocone, 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one, (-)-Dihydrocodeinone, Hydrocodon
compuesto químico
OverviewAI-generated
Hydrocodone is a chemical compound with the formula C₁₈H₂₁NO₃. Its IUPAC name is (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one. The substance has a melting point of 198 and a defined daily dose of 15.
Chemical properties include a mass of 299.152 and a weight of 299.4. The compound has an xlogp of 2.2 and a tpsa of 38.8. It contains zero hydrogen bond donors and four hydrogen bond acceptors, with a charge of 0.
Hydrocodone is referenced by 1,275 other encyclopedia articles.
Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.excretion
- Urine
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443251358
- Drug.image
- Hydrocodone skeletal.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Hydrocodone-Spartan-PM3-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 225
- Drug.tradename
- Hysingla ER, Zohydro ER
- Drug.MedlinePlus
- a601006
- Drug.DailyMedID
- Hydrocodone
- Drug.dependency_liability
- High
- Drug.addiction_liability
- High
- Drug.class
- Opioid
- Drug.routes_of_administration
- Clinical: By mouthOthers: Intranasal, rectal
- Drug.ATC_prefix
- R05
- Drug.ATC_suffix
- DA03
via Wikipedia infobox
Chemical data
- Formula
- C18H21NO3
- Molecular weight
- 299.4 g/mol
- IUPAC name
- (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
- SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
- InChIKey
- LLPOLZWFYMWNKH-CMKMFDCUSA-N
- XLogP
- 2.2
- Polar surface area
- 38.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1943
- Admin. routes
- oral
- Indications
- pain, eye disease, Cough, injury
via ChEMBL · EBI
Research
1,669 papers- Hydrocodone bitartrate for chronic pain.Drugs of today (Barcelona, Spain : 1998) · 2015
- Hydrocodone Bitartrate ER (Hysingla(®) ER): A Review in Chronic Pain.Clinical drug investigation · 2016
- Hydrocodone extended-release: pharmacodynamics, pharmacokinetics and behavioral pharmacology of a controversy.Pharmacological research · 2015
- Extended-release hydrocodone (Hysingla ER) for pain.The Medical letter on drugs and therapeutics · 2015
- Hydrocodone: does it have a role in palliative care?Journal of opioid management · 2010
via PubMed
Wikidata facts
- Has part
- oxygen
- Mass
- 299.152
- Has use
- medication
Show 11 more facts
- chemical formula
- C₁₈H₂₁NO₃
- subject has role
- antitussive
- medical condition treated
- cough
- isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4
- melting point
- 198
- canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)CC4
- World Health Organisation international non-proprietary name
- hydrocodone
- Commons category
- Hydrocodone
- defined daily dose
- 15
- found in taxon
- Papaver somniferum
- stylized name
- HYDROcodone
via Wikidata · CC0
Article · Español
La hidrocodona es un opioide derivado de la codeína, que se utiliza como analgésico vía oral para tratar el dolor moderado a severo y como antitusivo. Se puede encontrar en pastillas, jarabe o cápsulas, y es un narcótico que puede producir dependencia y un grave síndrome de abstinencia. La hidrocodona y los compuestos que la contienen se encuentran en el mercado en varias formas, bajo un gran número de marcas comerciales. Su venta fue aprobada en Estados Unidos en 1943 por la Administración de Alimentos y Medicamentos (FDA) estadounidense. En el 2014, la Drug Enforcement Administration (DEA) incluyó a la hidrocodona bajo la clasificación II de la Ley de Sustancias Controladas (Controlled Substances Act), lo que implica que tiene un alto potencial para el abuso, que su uso médico tiene severas restricciones, y que puede llevar a una dependencia psicológica o física grave.
Abstract from DBpedia / Wikipedia · CC BY-SA