IFNAR1
Sign in to saveAlso known as AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
Gene data
IFNAR1- Name
- interferon alpha and beta receptor subunit 1
- Type
- protein-coding
- Position
- 33,324,387–33,359,864 (+)
- Aliases
- AVP, CRF2-1, IFN-R-1, IFN-alpha-REC, IFNAR, IFNBR, IFRC, IMD106
- Ensembl
- ENSG00000142166
- RefSeq RNA
- NM_000629.3, NM_001384498.1, NM_001384499.1, NM_001384500.1, NM_001384501.1
- RefSeq protein
- NP_000620.2, NP_001371427.1, NP_001371428.1, NP_001371429.1, NP_001371430.1
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interferon alpha and beta receptor subunit 1
- Symbol
- IFNAR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:33,324,387-33,359,864
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 524
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3454
- genomic end
- 33359864
- genomic start
- 33324429
- chromosome
- human chromosome 21
- cytogenetic location
- 21q22.11
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
== Function ==
Excerpted from Wikipedia’s “IFNAR1” article, available under the CC BY-SA 4.0 licence.