IFNAR1
Sign in to saveAlso known as AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
Gene data
IFNAR1- Name
- interferon alpha and beta receptor subunit 1
- Type
- protein-coding
- Aliases
- AVP, CRF2-1, IFN-R-1, IFN-alpha-REC, IFNAR, IFNBR, IFRC, IMD106
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 524
- exact match
- identifiers.org/ncbigene/3454
- genomic end
- 33359864
- genomic start
- 33324429
- cytogenetic location
- 21q22.11
Sources (3)
via Wikidata · CC0
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Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
== Function ==