phosphatidylinositols
Also known as phosphatidylinositol
Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph von Scherer in the late 19th century. It was discovered in bacteria but later also found in eukaryotes, and was found to be a signaling molecule.
Research
107,963 papers- Preface.Biochimica et biophysica acta · 2015
- Phosphoinositide kinases.Biochemistry · 1990
- Phosphatidylinositol signalling reactions.Seminars in cell & developmental biology · 1998
- High-resolution phosphoinositide analysis.Methods in enzymology · 2026
- Phosphoinositide phosphorylation sans kinase.Nature cell biology · 2022
via PubMed
Article
9 sectionsContents
- History of phospatidylinositol
- Structure and chemistry
- Phosphoinositides
- Biosynthesis
- Metabolism
- Hydrolysis
- Phosphorylation
- References
- External links
Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph von Scherer in the late 19th century. It was discovered in bacteria but later also found in eukaryotes, and was found to be a signaling molecule.
The biomolecule can exist in nine different isomers. It is a lipid which contains a phosphate group, two fatty acid chains, and one inositol sugar molecule. Typically, the phosphate group has a negative charge (at physiological pH values). As a result, the molecule is amphiphilic.