آیوهگزول

Also known as Exypaque, Omnipaque 350, Omnipaque 140, Omnipaque, Omnipaque 300, Omnipaque 180, WIN-39424, Omnipaque 240

Iohexol, sold under the trade names Omnipaque and Iodaque among others, is a contrast agent used for X-ray imaging. This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computed tomography (CT scan). It is given by mouth, injection into a vein, or into a body cavity.

Key facts

Drug.Verifiedfields: changed
Drug.verifiedrevid: 461935422
Drug.image: Iohexol.svg
Drug.image_class: skin-invert-image
Drug.tradename: Iodaque, Hexopaque, Oraltag, others
Drug.DailyMedID: Iohexol
Drug.routes_of_administration: Intrathecal, intravascular, by mouth, intracavital, rectal
Drug.ATC_prefix: V08
Drug.ATC_suffix: AB02
Drug.legal_CA: Rx-only
Drug.legal_US: Rx-only
Drug.legal_status: Rx-only
Drug.protein_bound: Low
Drug.metabolism: Nil
Drug.elimination_half life: Variable
Drug.excretion: Kidney, unchanged
Drug.CAS_number: 66108-95-0
Drug.PubChem: 3730

via Wikipedia infobox

Chemical data

Formula: C19H26I3N3O9
Molecular weight: 821.1 g/mol
IUPAC name: 5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
SMILES: CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
InChIKey: NTHXOOBQLCIOLC-UHFFFAOYSA-N
XLogP: -3
Polar surface area: 200 Å²
H-bond donors: 8
H-bond acceptors: 9
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1985
Admin. routes: oral, parenteral, topical
Indications: HIV infection, Acute kidney injury, Renal insufficiency, kidney disease

via ChEMBL · EBI

Research

6,578 papers

Is Iohexol a Possible Method for Estimating Glomerular Filtration Rate?Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia · 2025
Toxicology of iohexol.Investigative radiology · 1985
Assessment of Iohexol Serum Clearance by LC-MS/MS with Isotopically Labeled Internal Standard.Methods in molecular biology (Clifton, N.J.) · 2024
Iohexol is an intestinal permeability marker in broilers under coccidiosis challenge.Poultry science · 2023
Iohexol.Acta radiologica. Supplementum · 1980

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 820.880323
Has use: medication

Show 6 more facts

chemical formula: C₁₉H₂₆I₃N₃O₉
canonical SMILES: CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
World Health Organisation international non-proprietary name: iohexol
Commons category: Iohexol
subject has role: essential medicine
legal status (medicine): boxed warning

Sources (4)

via Wikidata · CC0

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via Wikidata sitelinks · CC0