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EntityQ6085540· pop 9· linked from 2 articles

Isocomene is a sesquiterpene first isolated from the perennial herb southern goldenbush (Isocoma wrightii), from which it derives its name. Its unusual structure consisting of three fused cyclopentane rings was first described by Zalkow et al. in 1977. The first total synthesis of isocomene was published by M.C. Pirrung in 1979. The key steps are a photocatalyzed intramolecular [2 + 2] cycloaddition reaction followed by a rearrangement reaction which forms three contiguous chiral centers.

Wikidata facts

Mass
204.187801
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chemical formula
C₁₅H₂₄
isomeric SMILES
C[C@@H]1CC[C@@]2(C13CCC[C@]3(C=C2C)C)C
canonical SMILES
CC1CCC2(C13CCCC3(C=C2C)C)C
Commons category
Isocomene
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Isocomene is a sesquiterpene first isolated from the perennial herb southern goldenbush (Isocoma wrightii), from which it derives its name. Its unusual structure consisting of three fused cyclopentane rings was first described by Zalkow et al. in 1977. The first total synthesis of isocomene was published by M.C. Pirrung in 1979. The key steps are a photocatalyzed intramolecular [2 + 2] cycloaddition reaction followed by a rearrangement reaction which forms three contiguous chiral centers.

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