KATNB1
Sign in to saveAlso known as KAT, LIS6, katanin regulatory subunit B1
Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
Gene data
KATNB1- Name
- katanin regulatory subunit B1
- Type
- protein-coding
- Aliases
- KAT, LIS6
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4302
- exact match
- identifiers.org/ncbigene/10300
- genomic start
- 57735739
- genomic end
- 57757244
- cytogenetic location
- 16q21
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Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. KATNB1 is associated with microlissencephaly.