Structure via PubChem · Public domain (PubChem)
lasalocid
Sign in to saveLasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.
Chemical data
- Formula
- C34H54O8
- Molecular weight
- 590.8 g/mol
- IUPAC name
- 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-3-methyloxolan-2-yl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid
- SMILES
- CC[C@H]([C@@H]1[C@H](C[C@@](O1)(CC)[C@H]2CC[C@@]([C@@H](O2)C)(CC)O)C)C(=O)[C@@H](C)[C@H]([C@H](C)CCC3=C(C(=C(C=C3)C)O)C(=O)O)O
- InChIKey
- BBMULGJBVDDDNI-OWKLGTHSSA-N
- XLogP
- 6.4
- Polar surface area
- 134 Ų
- H-bond donors
- 4
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
995 papers- Biosynthetic machinery of ionophore polyether lasalocid: enzymatic construction of polyether skeleton.Current opinion in chemical biology · 2013
- Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins.Toxins · 2020
- Lasalocid: resistance and cross-resistance studies in Eimeria tenella-infected chicks.Poultry science · 1975
- New Hydrophilic Derivatives of Lasalocid and Their Complexes with Selected Metal Cations.Molecules (Basel, Switzerland) · 2023
- Comparison effect of lasalocid, diclazuril, probiotic and symbiotic on histomorpholical changes of small intestine induced by E. tenella.Veterinaria italiana · 2023
via PubMed
Wikidata facts
- Mass
- 590.382
Show 4 more facts
- canonical SMILES
- CCC(C1C(CC(O1)(CC)C2CCC(C(O2)C)(CC)O)C)C(=O)C(C)C(C(C)CCC3=C(C(=C(C=C3)C)O)C(=O)O)O
- chemical formula
- C₃₄H₅₄O₈
- isomeric SMILES
- CC[C@H]([C@@H]1[C@H](C[C@@](O1)(CC)[C@H]2CC[C@@]([C@@H](O2)C)(CC)O)C)C(=O)[C@@H](C)[C@H]([C@H](C)CCC3=C(C(=C(C=C3)C)O)C(=O)O)O
- found in taxon
- Streptomyces
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.
Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine.
Excerpted from Wikipedia’s “lasalocid” article, available under the CC BY-SA 4.0 licence.