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EntityQ24890013· pop 14· linked from 53 articles

Also known as Xenleta

Lefamulin, sold under the brand name Xenleta, is an antibiotic medication used it to treat adults with community-acquired bacterial pneumonia. It is taken by mouth or by injection into a vein.

Key facts

Drug.O
5
Drug.S
1
Drug.IUPAC_name
(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate
Drug.image
Lefamulin skeletal.svg
Drug.image_class
skin-invert-image
Drug.tradename
Xenleta
Drug.DailyMedID
Lefamulin
Drug.routes_of_administration
Intravenous, by mouth
Drug.legal_CA
Rx-only
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.CAS_number
1061337-51-6
Drug.ATC_prefix
J01
Drug.ATC_suffix
XX12
Drug.PubChem
25185057
Drug.DrugBank
DB12825
Drug.ChemSpiderID
32701544
Drug.ChEMBL
3291398

via Wikipedia infobox

Wikidata facts

Mass
507.30184453999993
Show 4 more facts
isomeric SMILES
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C
canonical SMILES
CC1CCC23CCC(=O)C2C1(C(CC(C(C3C)O)(C)C=C)OC(=O)CSC4CCC(CC4O)N)C
Commons category
Lefamulin
chemical formula
C₂₈H₄₅NO₅S
Sources (3)

via Wikidata · CC0

~3 min read

Encyclopedic overview

6 sections
Contents
  • Medical uses
  • Spectrum of activity
  • History
  • Society and culture
  • Legal status
  • References

{{Infobox drug | IUPAC_name = (1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate | image = Lefamulin skeletal.svg | image_class = skin-invert-image | alt = | caption =

| pronounce = | tradename = Xenleta | Drugs.com = | MedlinePlus = | DailyMedID = Lefamulin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = Intravenous, by mouth

Excerpted from Wikipedia’s “lefamulin” article, available under the CC BY-SA 4.0 licence.