Structure via PubChem · Public domain (PubChem)
lenperone
Sign in to saveLenperone (Elanone-V) is a typical antipsychotic of the butyrophenone chemical class. It was first reported as an anti-emetic in 1974, and its use in treatment of acute schizophrenia was reported in 1975. Related early antipsychotic agents include declenperone and milenperone.
Chemical data
- Formula
- C22H23F2NO2
- Molecular weight
- 371.4 g/mol
- IUPAC name
- 4-[4-(4-fluorobenzoyl)piperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
- SMILES
- C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCCC(=O)C3=CC=C(C=C3)F
- InChIKey
- WCIBOXFOUGQLFC-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 37.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 371.17
Show 3 more facts
- chemical formula
- C₂₂H₂₃F₂NO₂
- canonical SMILES
- C1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCCC(=O)C3=CC=C(C=C3)F
- Commons category
- Lenperone
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Lenperone (Elanone-V) is a typical antipsychotic of the butyrophenone chemical class. It was first reported as an anti-emetic in 1974, and its use in treatment of acute schizophrenia was reported in 1975. Related early antipsychotic agents include declenperone and milenperone.
Lenperone was never approved by the FDA for use in humans in the United States, but prior to 1989 it was approved for use in veterinary medicine for sedation.
Excerpted from Wikipedia’s “lenperone” article, available under the CC BY-SA 4.0 licence.