Structure via PubChem · Public domain (PubChem)
leukotriene c4
Sign in to saveAlso known as LTC4, 5S-hydroxy,6R-(S-glutathionyl),7E,9E,11Z,14Z-eicosatetraenoic acid, LTC (sub 4), 5S,6R-Ltc(sub 4), (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, (5S,6R,7E,9E,11Z,14Z)-6-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid, (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-Glycine
chemical compound
Chemical data
- Formula
- C30H47N3O9S
- Molecular weight
- 625.8 g/mol
- IUPAC name
- (5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
- SMILES
- CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
- InChIKey
- GWNVDXQDILPJIG-NXOLIXFESA-N
- XLogP
- 0.7
- Polar surface area
- 242 Ų
- H-bond donors
- 7
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
3,874 papers- Myocardial reperfusion injury exacerbation due to ALDH2 deficiency is mediated by neutrophil extracellular traps and prevented by leukotriene C4 inhibition.European heart journal · 2024
- Leukotriene C4 synthase.Journal of lipid mediators and cell signalling · 1995
- Leukotriene C4 synthesis deficiency: a member of a probably underdiagnosed new group of neurometabolic diseases.European journal of pediatrics · 2000
- Transport of leukotriene C4 and structurally related conjugates.Vitamins and hormones · 2002
- Leukotriene C(4) synthase.Prostaglandins, leukotrienes, and essential fatty acids · 2003
via PubMed
Wikidata facts
- Subclass of
- leukotriene
- Mass
- 625.303
Show 5 more facts
- chemical formula
- C₃₀H₄₇N₃O₉S
- canonical SMILES
- CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
- subject has role
- primary metabolite
- isomeric SMILES
- CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
- found in taxon
- Homo sapiens
via Wikidata · CC0