LGALS13
Sign in to saveAlso known as GAL13, PLAC8, PP13, galectin 13
Placental protein 13 (PP13, also known as galectin-13) is a protein that in humans is encoded by the LGALS13 gene.
Gene data
LGALS13- Name
- galectin 13
- Type
- protein-coding
- Position
- 39,602,490–39,607,476 (+)
- Aliases
- GAL13, PLAC8, PP13
- Ensembl
- ENSG00000105198
- RefSeq RNA
- NM_013268.3, XM_011526874.3, XM_024451474.2, XM_054320753.1, XM_054320754.1
- RefSeq protein
- NP_037400.1, XP_011525176.2, XP_024307242.1, XP_054176728.1, XP_054176729.1
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
galectin 13
- Symbol
- LGALS13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:39,602,490-39,607,476
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49329
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29124
- genomic end
- 39607474
- genomic start
- 39602524
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.2
- expressed in
- hypothalamus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Structure and function
- Clinical significance
- References
- External links
Placental protein 13 (PP13, also known as galectin-13) is a protein that in humans is encoded by the LGALS13 gene.
==Structure and function== It is composed of two identical subunits which are held together by disulfide bonds. The monomer of this protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family, but it could not bind beta-galactoside. This is because the ligand binding site is lack of key residue for binding beta-galactoside. It is a galectin-like protein.
Excerpted from Wikipedia’s “LGALS13” article, available under the CC BY-SA 4.0 licence.