Structure via PubChem · Public domain (PubChem)
lindaan
Sign in to saveAlso known as Gexane, Kwell, Gamene, Quellada, Scabene, gamma-BHC, gamma-1,2,3,4,5,6-Hexachlorocyclohexane, Gammaxene
chemische verbinding
OverviewAI-generated
Lindane, also identified by the IUPAC name 1,2,3,4,5,6-hexachlorocyclohexane, is a chemical compound with the formula C₆H₆Cl₆. Its molecular mass is listed as 287.8601 in one source and 290.8 in another. The substance has a density of 1.85, a melting point of 235, and a boiling point of 614. It exhibits a vapor pressure of 0.00001 and a solubility of 0.001.
In terms of safety, the immediately dangerous to life or health level is 50, while the time-weighted average exposure limit is 0.5. The compound has a xlogp value of 3.8 and a topological polar surface area of 0. It contains no hydrogen bond donors or acceptors and carries a charge of 0. A PubMed search for lindane yields 7310 results, and the subject is referenced by 738 other encyclopedia articles.
Synthesized by Vinony from 27 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.verifiedrevid
- 457117932
- Drug.IUPAC_name
- (1r,2R,3S,4r,5R,6S)-1,2,3,4,5,6-hexachlorocyclohexane
- Drug.image
- Gamma-hexachlorocyclohexane.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 150px
- Drug.image2
- Lindane (chair) molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 170
- Drug.alt2
- Ball-and-stick model of the lindane molecule (chair conformation)
- Drug.MedlinePlus
- a682651
- Drug.pregnancy_category
- C
- Drug.legal_status
- Production and agricultural use is banned in the 182 countries that are Parties to the Stockholm Convention, but pharmaceutical use is allowed as a second-line treatment for scabies and lice
- Drug.routes_of_administration
- Topical
- Drug.protein_bound
- 91%
- Drug.metabolism
- Hepatic cytochrome P-450 oxygenase system
- Drug.elimination_half life
- 18 hours
- Drug.CAS_number
- 58-89-9
- Drug.ATC_prefix
- P03
via Wikipedia infobox
Chemical data
- Formula
- C6H6Cl6
- Molecular weight
- 290.8 g/mol
- IUPAC name
- 1,2,3,4,5,6-hexachlorocyclohexane
- SMILES
- C1(C(C(C(C(C1Cl)Cl)Cl)Cl)Cl)Cl
- InChIKey
- JLYXXMFPNIAWKQ-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 0 Ų
- H-bond donors
- 0
- H-bond acceptors
- 0
- Formal charge
- 0
via PubChem
Research
7,310 papers- [Lindane].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1995
- Lindane.Reviews of environmental contamination and toxicology · 1988
- Lessons from the genomes of lindane-degrading sphingomonads.Environmental microbiology reports · 2019
- Lindane-induced liver oxidative stress.Free radical biology & medicine · 1990
- Lindane toxicity: a comprehensive review of the medical literature.Pediatric dermatology · 2012
via PubMed
Article · Nederlands
Lindaan of hexachloorcyclohexaan is een verbinding die vooral als insecticide werd/wordt gebruikt. Sinds 1969 is de productie wereldwijd sterk gedaald vanwege de hoge giftigheid. Lindaan is zeer toxisch voor waterorganismen, wordt langzaam afgebroken en accumuleert in de voedselketen (vooral bij vis). Lindaan is ontdekt door Teunis van der Linden, die aan de Universiteit van Amsterdam heeft gewerkt aan de chlorering van alkanen, in het bijzonder van cyclohexaan. Van de verbinding zijn 3 stereo-isomeren bekend: α-, β- en γ-lindaan.
Abstract from DBpedia / Wikipedia · CC BY-SA