Structure via PubChem · Public domain (PubChem)
lofendazam
Sign in to saveLofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam.
Chemical data
- Formula
- C15H13ClN2O
- Molecular weight
- 272.73 g/mol
- IUPAC name
- 7-chloro-5-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-4-one
- SMILES
- C1CNC2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=CC=C3
- InChIKey
- IUJQOUHDFKALCY-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 32.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 272.072
Show 2 more facts
- chemical formula
- C₁₅H₁₃ClN₂O
- canonical SMILES
- C1CNC2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=CC=C3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Lofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam.
Lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. It is an active metabolite of another benzodiazepine, arfendazam.
Excerpted from Wikipedia’s “lofendazam” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0