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GeneQ18037283· pop 5· linked from 487 articles

LPAR3

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Also known as EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3, lysophosphatidic acid receptor 3

Lysophosphatidic acid receptor 3 also known as LPA3 is a protein in humans that is encoded by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Gene data

LPAR3
Name
lysophosphatidic acid receptor 3
Type
protein-coding
Position
84,811,541–84,893,540 (−)
Aliases
EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3
Ensembl
ENSG00000171517
RefSeq RNA
NM_012152.3, XM_054335709.1, XM_054335710.1, XM_054335711.1
RefSeq protein
NP_036284.1, XP_054191684.1, XP_054191685.1, XP_054191686.1

This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Rap1 signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)GPCR downstream signallingG alpha (q) signalling events

via MyGene.info

Gene · Ensembl

lysophosphatidic acid receptor 3

Symbol
LPAR3
Biotype
Protein coding
Organism
Homo sapiens
Location
1:84,811,541-84,893,540
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
8123
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/23566
genomic end
84893206
genomic start
85277285
chromosome
human chromosome 1
cytogenetic location
1p22.3
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

7 sections
Contents
  • Function
  • Evolution
  • [[Sequence homology|Paralogues]]
  • See also
  • References
  • Further reading
  • External links

Lysophosphatidic acid receptor 3 also known as LPA3 is a protein in humans that is encoded by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

== Function ==

Excerpted from Wikipedia’s “LPAR3” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0