LZTR1
Sign in to saveAlso known as BTBD29, LZTR-1, SWNTS2, NS10, leucine-zipper-like transcription regulator 1, leucine zipper like transcription regulator 1, NS2
thumb|Leucine Zipper Transcription Regulator Protein Structure Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.
Gene data
LZTR1- Name
- leucine zipper like post translational regulator 1
- Type
- protein-coding
- Position
- 20,981,979–20,999,037 (+)
- Aliases
- BTBD29, LZTR-1, NS10, NS2, SWNTS2
- Ensembl
- ENSG00000099949
- RefSeq RNA
- NM_006767.4
- RefSeq protein
- NP_006758.2
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
leucine zipper like post translational regulator 1
- Symbol
- LZTR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:20,981,979-20,999,037
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4925
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8216
- genomic start
- 20982269
- chromosome
- human chromosome 22
- genomic end
- 20999032
- cytogenetic location
- 22q11.21|22q11.1-q11.2
Sources (4)
via Wikidata · CC0
~5 min read
Encyclopedic overview
8 sectionsContents
- Function
- Gene
- Mutations
- DiGeorge Syndrome
- Noonan syndrome
- Schwannomatosis
- References
- Further reading
thumb|Leucine Zipper Transcription Regulator Protein Structure Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.
The LZTR1 gene provides instructions for making a protein among the class of the superfamily broad complex, tamtrack & brick-a-bac / poxvirus and zinc finger (BTB/POZ). The superfamily of proteins has a wide range of functions including chromatin condensation during conformation of the cell cycle. Other names associated with the LZTR gene are: BTBD29, LZTR-1, NS10, NS2, SWNTS2. This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex.
Excerpted from Wikipedia’s “LZTR1” article, available under the CC BY-SA 4.0 licence.