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mebroqualone

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mebroqualone

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Mebroqualone (MBQ) is a quinazolinone-class GABAergic and is an analogue of mecloqualone that has similar sedative and hypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of the GABAa receptor. It was originally synthesized in the 1960s Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring. It was made illegal in Germany in 1998 but little other information is available. It would appear that this compound was sold on the black market in Germany as a designer drug analogue of mecloqualone.

Chemical data

Formula
C15H11BrN2O
Molecular weight
315.16 g/mol
IUPAC name
3-(2-bromophenyl)-2-methylquinazolin-4-one
SMILES
CC1=NC2=CC=CC=C2C(=O)N1C3=CC=CC=C3Br
InChIKey
NBUSAPJNASSKBP-UHFFFAOYSA-N
XLogP
2.8
Polar surface area
32.7 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
314.005
Show 2 more facts
chemical formula
C₁₅H₁₁BrN₂O
canonical SMILES
CC1=NC2=CC=CC=C2C(=O)N1C3=CC=CC=C3Br
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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Mebroqualone (MBQ) is a quinazolinone-class GABAergic and is an analogue of mecloqualone that has similar sedative and hypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of the GABAa receptor. It was originally synthesized in the 1960s Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring. It was made illegal in Germany in 1998 but little other information is available. It would appear that this compound was sold on the black market in Germany as a designer drug analogue of mecloqualone.

== See also == Methaqualone Afloqualone Etaqualone Methoxyqualone Methylmethaqualone Mecloqualone Cloroqualone Diproqualone Gamma-Aminobutyric acid

Excerpted from Wikipedia’s “mebroqualone” article, available under the CC BY-SA 4.0 licence.

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