Structure via PubChem · Public domain (PubChem)
مفروزید
Sign in to saveMefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.
Chemical data
- Formula
- C13H19ClN2O5S2
- Molecular weight
- 382.9 g/mol
- IUPAC name
- 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide
- SMILES
- CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
- InChIKey
- SMNOERSLNYGGOU-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 124 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
100 papers- Mefruside: a preliminary report of its pharmacological properties and therapeutic efficacy in oedema and hypertension.Drugs · 1974
- Mefruside--A new diuretic.Drug and therapeutics bulletin · 1972
- Trial of mefruside.British medical journal · 1972
- Trial of mefruside.British medical journal · 1972
- Antihypertensive mechanism of diuretics based on pressure-natriuresis relationship.Hypertension (Dallas, Tex. : 1979) · 1996
via PubMed
Wikidata facts
- Mass
- 382.042
Show 6 more facts
- chemical formula
- C₁₃H₁₉ClN₂O₅S₂
- canonical SMILES
- CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
- subject has role
- diuretic
- medical condition treated
- arterial hypertension
- Commons category
- Mefruside
- defined daily dose
- 25
via Wikidata · CC0