Structure via PubChem · Public domain (PubChem)
mefruside
Sign in to saveMefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.
Chemical data
- Formula
- C13H19ClN2O5S2
- Molecular weight
- 382.9 g/mol
- IUPAC name
- 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide
- SMILES
- CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
- InChIKey
- SMNOERSLNYGGOU-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 124 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
100 papers- Mefruside: a preliminary report of its pharmacological properties and therapeutic efficacy in oedema and hypertension.Drugs · 1974
- Mefruside--A new diuretic.Drug and therapeutics bulletin · 1972
- Trial of mefruside.British medical journal · 1972
- Trial of mefruside.British medical journal · 1972
- Antihypertensive mechanism of diuretics based on pressure-natriuresis relationship.Hypertension (Dallas, Tex. : 1979) · 1996
via PubMed
Wikidata facts
- Mass
- 382.042
Show 6 more facts
- chemical formula
- C₁₃H₁₉ClN₂O₅S₂
- canonical SMILES
- CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
- subject has role
- diuretic
- medical condition treated
- arterial hypertension
- Commons category
- Mefruside
- defined daily dose
- 25
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Mefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.
It was developed by Bayer A.G. and is sold under the tradename Baycaron.
Excerpted from Wikipedia’s “mefruside” article, available under the CC BY-SA 4.0 licence.