Structure via PubChem · Public domain (PubChem)
torasemide
Also known as AC-4464, AC4464, BM-02015, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide, 1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, torsemide
Torasemide, also known as torsemide, is a diuretic medication used to treat fluid overload due to heart failure, kidney disease, and liver disease. It is a less preferred treatment for high blood pressure. It is taken by mouth or by injection into a vein.
Chemical data
- Formula
- C16H20N4O3S
- Molecular weight
- 348.4 g/mol
- IUPAC name
- N-[4-(3-methylanilino)pyridin-1-ium-3-yl]sulfonyl-N'-propan-2-ylcarbamimidate
- SMILES
- CC1=CC(=CC=C1)NC2=C(C=[NH+]C=C2)S(=O)(=O)NC(=NC(C)C)[O-]
- InChIKey
- NGBFQHCMQULJNZ-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 116 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
698 papers~3 min read
Article
6 sectionsContents
- Medical uses
- Adverse effects
- Chemistry
- Names
- Veterinary uses
- References
Torasemide, also known as torsemide, is a diuretic medication used to treat fluid overload due to heart failure, kidney disease, and liver disease. It is a less preferred treatment for high blood pressure. It is taken by mouth or by injection into a vein.
Common side effects include headache, increased urination, diarrhea, cough, and dizziness. Other side effects may include hearing loss and low blood potassium. Torasemide is a sulfonamide and loop diuretic. Use is not recommended in pregnancy or breastfeeding. It works by decreasing the reabsorption of sodium by the kidneys.