mepartricin

Also known as mepartricin A

Mepartricin is a macrolide polyene compound that is useful for urethra, prostate, and bladder function. It has been studied for use in treating chronic pelvic pain syndrome and benign prostatic hyperplasia.

Research

108 papers

Mepartricin long-term administration regulates steroid hormone and adrenergic receptor concentrations in the prostate of aged rats.Journal of veterinary pharmacology and therapeutics · 2006
Effect of mobile phase pH on liquid chromatography retention of mepartricin related compounds and impurities as support to the structural investigation by liquid chromatography-mass spectrometry.Journal of pharmaceutical and biomedical analysis · 2022
Estrogen suppression as a pharmacotherapeutic strategy in the medical treatment of benign prostatic hyperplasia: evidence for its efficacy from studies with mepartricin.Wiener klinische Wochenschrift · 1998
The structure of mepartricin A and mepartricin B.The Journal of antibiotics · 1980
[Mepartricin as medical treatment of benign prostatic hypertrophy].Journal d'urologie · 1993

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Wikidata facts

Mass: 1140.598129

Show 3 more facts

chemical formula: C₆₀H₈₈N₂O₁₉
isomeric SMILES: C[C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)OC\2CC3C(C(CC(O3)(CC(CC(CC(CC(CC(=O)CC(CC(=O)OC(C(/C=C/C=C/C=C\C=C/C=C/C=C/C=C2)C)C(C)CCC(CC(=O)C4=CC=C(C=C4)NC)O)O)O)O)O)O)O)O)C(=O)OC)O)N)O
canonical SMILES: CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(CC(CC(CC(=O)CC(CC(=O)OC1C(C)CCC(CC(=O)C3=CC=C(C=C3)NC)O)O)O)O)O)O)O)O)C(=O)OC)OC4C(C(C(C(O4)C)O)N)O

Sources (1)

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Encyclopedic overview

2 sections

Contents

Pharmacodynamics
References

==Pharmacodynamics==

Excerpted from Wikipedia’s “mepartricin” article, available under the CC BY-SA 4.0 licence.

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